Concurrent scientific working group session I
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| Axon 1*: |
Pluripotency and embryonic stem cells
(chair: Mathias Treier / James Adjave) |
| 09:30 – 09:40 |
Introduction |
| 09:40 – 10:00 |
T01 - Loss of Myc activity induces cellular dormancy in ES cells cultured in 2i mimicking the status of diapause embryos
Roberta Scognamiglio; German Cancer Research Center, Heidelberg |
| 10:00 – 10:20 |
T02 - Epigenetic regulation of lineage commitment
Gunnar Schotta; Adolf Butenandt Institute, LMU Munich
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| 10:20 – 10:40 |
T03 - Mll2 is the H3K4 trimethyltransferase for bivalent promoters in mouse embryonic stem cells
A. Francis Stewart; Technical University Dresden |
| 10:40 – 11:00 |
Group discussion
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|
| Axon 2: |
Cancer stem cells in solid tumors
(chair: Andreas Trumpp / Thomas Brabletz)
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| 09:30 – 09:40 |
Introduction |
| 09:40 – 10:00 |
T04 - The KC/IL8-mTOR axis activates stem cell maintenance and chemotherapy resistance of hepatic tumor-initiating cells
Uta Kossatz-Böhlert; University Tübingen
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| 10:00 – 10:20 |
T05 - The role of EVI1 in breast cancer cells
Hui Wang; University Hospital Basel, Switzerland
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| 10:20 – 10:40 |
T06 - Patient derived models for pancreatic cancer reveal four molecular subtypes associated with differential drug response and clinical outcome
Elisa Noll; HI-STEM, Heidelberg
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| 10:40 – 11:00 |
Group discussion |
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|
| Dendrit 2/3: |
Stem cells in tissues of meso- and endodermal origin
(chair: Thomas Braun / Heiko Lickert)
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| 09:30 – 09:40 |
Introduction |
| 09:40 – 10:00 |
T07 - A lentiviral RNAi screen against the muscle stem cell proteome identifies novel regulators governing muscle regeneration
Johnny Kim; MPI f. Heart and Lung Research, Bad Nauheim
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| 10:00 – 10:20 |
T08 - Direct lineage conversion of liver to pancreas
Francesca M. Spagnoli; Max Delbrück Center, Berlin
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| 10:20 – 10:40 |
T09 - Early Growth Response transcription factors Egr1 and Egr2 regulate lineage commitment of bone marrow mesenchymal stromal progenitors
Konstantinos Anastassiadis; BIOTEC, Technical University Dresden
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| 10:40 – 11:00 |
Group discussion
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| 11:00 – 11:30 |
Coffee break / Industry exhibition |
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Concurrent strategic working group session A
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| Axon 1: |
Career development (chairs: Insa Schröder / NN)
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| 11:30 – 11:50 |
I1 – Alternative career pathways for life scientists
Thorsten Abs; academics GmbH, Hamburg
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| 11:50 – 12:30 |
Group / panel discussion
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| Axon 2: |
Funding programs/policies (chairs: Albrecht Müller / Ulrich Martin) |
| 11:30 – 11:50 |
I2 - Horizon 2020 - News on EU research funding
Jürgen Sautter; European Commission, Brussels, Belgium
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| 11:50 – 12:30 |
Group / panel discussion
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|
| Dendrit 2/3: |
Outreach activities and public perception of stem cell therapies (chair: Tobias Cantz / Ira Herrmann)
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| 11:30 – 11:40 |
Introduction (Tobias Cantz)
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| 11:40 – 11:55 |
I3: EuroStemCell Toolkit for Public Engagement: Information, Education, Conversation
Emma Kemp, EuroStemCell, Edinburgh, United Kingdom
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| 11:55 – 12:10 |
I4: Ethical aspects of innovative therapies
Gisela Badura-Lotter, University Ulm |
| 12:10 – 12:30 |
Group/panel discussion |
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| 12:30 – 13:30 |
Lunch buffet / Industry exhibition
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| Concurrent strategic working group session B |
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| Axon 1: |
Stem cell technologies (chair: Frank Emmrich / Andreas Bosio) |
| 13:30 – 13:50 |
I5: Stem cell technologies
Andreas Bosio; Miltenyi, Berg. Gladbach, and Frank Emmrich; University Leipzig |
| 13:50 – 14:30 |
Group/panel discussions |
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| Axon 2: |
Clinical trials and regulatory affairs (chair: Torsten Tonn / Andreas Kurtz) |
| 13:30 – 13:50 |
I6: Implementation of cell- and gene therapy for clinical application: challenges and regulatory requirements
Christine Günther; Apceth GmbH & Co. KG, Ottobrunn |
| 13:50 – 14:30 |
Group/panel discussions |
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| 14:30 – 14:45 |
Short break
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| Concurrent scientific working group session II |
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| Axon 1: |
Stem cells in regenerative therapies (chair: Michael Cross / Ulrich Martin) |
| 14:45 – 14:55 |
Introduction |
| 14:55 – 15:15 |
T10 - Transplantation of genetically corrected human iPSC-derived neural stem cells in a mouse model of metachromatic leukodystrophy
Jonas Doerr; Institute of Reconstructive Neurobiology, Bonn |
| 15:15 – 15:35 |
T11 - MicroRNA-199a-5p: A novel regulator of differentiation of hepatocytes from embryonic stem cells
Selina Möbus; REBIRTH, MH Hannover |
| 15:35 – 15:55 |
T12 - Successful treatment of therapy-refractory acute Graft-versus-Host disease with mesenchymal stem cell-derived exosomes
Bernd Giebel; Institute for Transfusion Medicine, Essen |
15:55 – 16:15
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Group discussion |
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| Axon 2: |
Programing and reprograming (chair: Micha Drukker / Frank Edenhofer) |
| 14:45 – 14:55 |
Introduction |
| 14:55 – 15:15 |
T13 - Analysis of signaling framework governing cardiac specification of human pluripotent stem cells
Boris Greber; MPI f. molecular Biomedicine, Münster |
| 15:15 – 15:35 |
T14 - Generation of mature megakaryocytes from human pluripotent stem cells by a transcription factor mediated forward programming approach
Thomas Moreau; University of Cambridge, United Kingdom |
| 15:35 – 15:55 |
T15 - A DNA methylation motifs discovery algorithm reveals the crosstalk among DNA methylation, transcription factors and histone marks in pluripotent cells
Marcos J. Arauzo-Bravo; MPI f. molecular Biomedicine, Münster |
| 15:55 – 16:15 |
Group discussion
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| Dendrit 2/3: |
Stem cells in tissues of neural and non-neural ectoderm (chair: Walter Birchmeier / Ana Martin-Villalba) |
| 14:45 – 14:55 |
Introduction |
| 14:55 – 15:15 |
T16 - Clonal lineage tracing of adult neural stem cells reveals features of adult neurogenesis
Filippo Calzolari; Helmholtz Center Munich |
| 15:15 – 15:35 |
T17 - The inflammatory gene AKNA, an at-hook containing transcription factor, regulates differentiation and survival of neural stem cells
Pia Johansson; Helmholtz Center Munich |
| 15:35 – 15:55 |
T18 - Oligodendrogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt
Benedikt Berninger; University Mainz |
| 15:55 – 16:15 |
Group discussion |
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| 16:15 - 18:45 |
Poster session II: P095 – P193
P095 – P116: HSCs and stem cells in hematopoietic malignancies
P117 – P128: Cancer stem cells in solid tumors
P129 – P166: Stem cells in regenerative therapies
P167 – P193: Stem cells in disease modeling and drug development |
| 18:45 – 19:30 |
Dinner buffet |
| 19:30 – 21:00 |
Convention of GSCN members |
| 21:00 – 22:00 |
Informal GSCN get-together (MDC.C Foyer) |